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KMID : 1038920150140020115
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Annals of Optometry and Contact Lens
2015 Volume.14 No. 2 p.115 ~ p.118
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A Case of Interdigital Skin Hyperpigmentation of the Hand Following the Use of Travoprost
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Park Min-Ji
Lim Sung-A
Kim Man-Soo
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Abstract
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Purpose: To report a case of interdigital skin hyperpigmentation of the hand following the use of travoprost.
Case summary: 0.004% travoprost was administered to a 57-year-old man to treat secondary glaucoma that occurred after keratoplasty in his both eyes. After 3 weeks of treatment with 0.004% travoprost. We detected the appearance of skin hyperpigmentation in both eyelids and in the interdigital skin of both hands. Thus, to establish whether 0.004% travoprost was the cause of the hyperpigmentation, we discontinued 0.004% travoprost and observed for a decrease in the amount of pigmentation. The hyperpigmentation of both eyelids and interdigital skin markedly decreased at 1 and 5 months, respectively, after the discontinuation of 0.004% travoprost.
Conclusions: Eyelid hyperpigmentation is a commonly known side effect of prostaglandin analogs. The type of interdigital skin hyperpigmentation reported here is a very rare side effect of 0.004% travoprost, highlighting the importance of this first case report from Korea.
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KEYWORD
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Hyperpigmentation, Prostaglandine analogue, Side effect, Travatan®, Travoprost
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